The Infectious Disease research group, led by Dr. Sameh Soliman and Postdoc Rania Hamdy, examined the structural characteristics and virulence factor of SARS-CoV-2 infections to design a potential therapeutic strategy, receiving a one million AED grant from Sandooq Al-Watan, resulting in two patents, several publications, and multiple awards including Sharjah Islamic Bank Award and second place at ESCM for a professional poster presentation; their findings revealed two compounds with superior in vitro antiviral activity against SARS-CoV-2, showing dual inhibition by targeting viral invasion through S-protein cleavage with the host protease TMPRSS2 and viral replication through RNA-dependent RNA polymerase (RdRp), enhancing phagocytosis and meeting drug-likeness criteria with promising physiochemical and pharmacokinetic features.