The immune system's everyday job is to protect the body from intruders such as viruses, allergens, and any foreign substances that may harm the cells." Cancer cells are moving target that constantly find ways to dodge immune system’s defenses. Immunotherapy is a very effective treatment for cancer that works by either training the immune system so it can do more to find and kill cancer cells or by helping the body to produce cancer fighting immune cells that effectively locate and destroy cancer cells. CAR-T Cell therapy, a form of immunotherapy that generated a substantial excitement among researchers and oncologists since it was approved by food and drug administration in 2017, as it showed its ability to eradicate very advanced leukemias and lymphomas. Currently available CAR-T Cell therapy are customized for each individual patient. As each cancer cell has different antigen present on its surface, for example, in certain kinds of leukemia and lymphoma,cancer cells have an antigen called CD-19 , CAR T-Cell helps to orchestrate the immune response and directly kill cancerous cells.

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